Sedating effect of antihistamine Free one on one sex chat foom
Histamine produces increased vascular permeability, causing fluid to escape from capillaries into tissues, which leads to the classic symptoms of an allergic reaction — a runny nose and watery eyes. Antihistamines suppress the histamine-induced wheal response (swelling) and flare response (vasodilation) by blocking the binding of histamine to its receptors or reducing histamine receptor activity on nerves, vascular smooth muscle, glandular cells, endothelium, and mast cells.
Itching, sneezing, and inflammatory responses are suppressed by antihistamines that act on H1-receptors.
Diphenhydramine and doxylamine have anticholinergic properties that make them poor choices for older adults.
Sedating antihistamines also have significant antimuscarinic activity and should be used with caution in patients with prostatic hypertrophy, urinary retention and angle-closure glaucoma.In fact, most over-the-counter sleep aids contain antihistamines.These products are intended to be used for only two to three nights at a time, however, such as when stress, travel or other disruptions keep you awake.Drowsiness is one of the major side effects of some antihistamines, such as diphenhydramine (Benadryl) and doxylamine succinate (the antihistamine found in Nyquil).And because of their powerful sedating qualities, antihistamines are also the active ingredients found in numerous over-the-counter sleep aids. The story begins with histamines, which are chemical compounds that play a couple of roles in the body, though they're best known for their involvement in the body's local immune responses.